NSAID-Induced GI
Toxicity
Updates in the Management
of Chronic Constipation
Effective Management
of Ulcerative Colitis


Diagnosis and Management of IBS
Purpose
Irritable bowel syndrome (IBS) is the most common diagnosis seen by gastroenterologists; IBS accounts for greater than 10% of all primary-care visits. As understanding of the pathophysiology behind IBS has evolved, the diagnosis, work-up and treatment of the syndrome have become more rational and more effective.


 
Program Overview
This program will discuss current thinking on the pathophysiology, diagnostic criteria and treatment options for IBS. It will discuss the epidemiology of IBS with special reference to the degree to which IBS is underdiagnosed, its economic costs and its effect on patients' quality of life. The evolving role of enteric neurotransmitters in the pathophysiology of IBS will be addressed and various IBS diagnostic criteria will be described. Treatments, both current and upcoming, will be reviewed, with an emphasis on evidence-based clinical practice guidelines.


 
Audience
This program has been specifically developed to update gastroenterologists and primary care physicians about the most current rationales behind the treatment of IBS.


 
Learning Objectives
Following completion of this CME activity, participants should be better able to:
  • Discuss the current data regarding the epidemiology of IBS
  • Identify current diagnostic criteria and work-up procedures for IBS
  • Discuss current theories regarding the pathophysiology of IBS
  • Identify current and future evidence-based treatment options for IBS


 
Faculty
David A. Katzka, MD
Associate Professor of Medicine
University of Pennsylvania School of Medicine
>> Read Biography

Emeran A. Mayer, MD
Professor of Medicine, Physiology and Psychiatry
UCLA David Geffen School of Medicine
>> Read Biography

Charlene M. Prather, MD
Associate Professor of Internal Medicine
Saint Louis University School of Medicine
>> Read Biography



 
Faculty Disclosure Information

In accordance with the Accreditation Council for Continuing Medical Education Standards for Commercial Support, faculty members for this activity were each asked to complete financial disclosure forms. Disclosures are provided below.

David A. Katzka, MD
Speakers' Bureau: Lectures: Novartis Pharmaceuticals

Emeran A. Mayer, MD
Consultant: AstraZeneca
Grant/Research Support: GSK, pre-clinical; Novartis Pharmaceuticals, pre-clinical and clinical; Microbia, pre-clinical

Charlene M. Prather, MD
Consultant: Novartis Pharmaceuticals Corporation, Solvay, PAR
Grant/Research Support: AstraZeneca
Speakers' Bureau: Lectures: Novartis Pharmaceuticals



 
Software Requirements
Internet Explorer (4.0 or greater), Windows 98 and Windows Media Player (7.0 or greater), or Adobe Acrobat (5.0 or greater)


 
Release Date
May 15, 2004


 
Expiration Date
May 15, 2006


 
Fee
Free-of-charge


 


 
Sponsorship and Support
Sponsored by the AGA. Supported through an unrestricted educational grant from Solvay Pharmaceuticals, Inc.


 
Program Segments
Irritable Bowel Syndrome: Epidemiology
  • Epidemiology
  • Effect on Quality of Life
  •   Key Clinical Issues: What Is the Role of Diminished Quality of Life in Beginning Treatment for IBS? What Is the Role of the Doctor-Patient Relationship in Diagnosing and Treating IBS?
    Irritable Bowel Syndrome: Pathophysiology
  • Pathophysiology
  • Anatomy
  • Key Role of Serotonin
  •   Key Clinical Issues: Does Serotonin Account for the Triad of IBS Pathophysiology: Altered Gut Motility, Visceral Hypersensitivity and Dysregulation of the Brain-Gut Axis? Irritable Bowel Syndrome: Functional Bowel Disorder or Neurologic Bowel Disease?
    Irritable Bowel Syndrome: Diagnosis
  • Diagnostic Criteria
  • Accuracy of the Diagnostic Criteria
  • Evidence-based Clinical Practice Guidelines for IBS
  •   Key Clinical Issues: What Is the Role of the Serotonin Agents in a Therapeutic Trial for IBS? Should Physicians Be Concerned Regarding False Negatives in the Diagnostic Work-up of IBS? Does the Prevalence of Organic Disease Differ Between Patients with IBS and the General Population?
    Irritable Bowel Syndrome: Treatment
  • Current AGA Recommendations About Treatment of IBS
  • Current Status of Clinical Trials in IBS
  •   Key Clinical Issues: Evidence-based Management of Irritable Bowel Syndrome: Has It Changed How You Treat IBS? What Is the Best Approach: Global Symptom Relief or Symptomatic Treatment of IBS? What Targets, Other Than Serotonin, Might Play a Vital Role in the Etiology of IBS?





     


     


     
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